Catalyze

Transformative

Investments

in the biotech industry

Our impact

CTI’s impact goes beyond delivering top-tier returns to our investors – Our portfolio companies have brought life-saving treatments to thousands of patients and fueled the growth of the local innovation ecosystem.

20+

Years in business

Multiple funds raised

30+

Investments

Therapeutic & Modality Agnostic

5

Regulatory approvals

10+ clinical trials

6

Companies created

10+

Exits

40% hit rate

100s

Jobs created

About us

More than an investor - we are a Company Builder that catalyzes nascent ideas and assets into investable, scalable, and marketable biotech companies. The CTI advantages are:

Enduring Value Creation Thesis

Strategic buyers will pay a premium to acquire biotech companies  with best-in-class assets or platform

Differentiated Investment strategy

Dual pronged approach that focuses on both long-term value creation and expedited exit timeline

Purposeful Portfolio Management

Steer investments towards a meaningful exit by leveraging deep industry expertise and expansive network

Meet our team

An experienced team with a proven track record and the complementary skillset to take biotech investments from inception to inflection.

Portfolio Companies

Active Companies

See portfolio
Ability Pharma has a first-in-class autophagy driven treatment for metastatic pancreatic cancer, one of the deadliest cancers, and its interim blinded Phase 2b data suggested a significant improvement over the current standard of care.
Aeovian is a clinical-stage biotherapeutics company developing mTORC1-specific inhibitors.
DalCor was created based on a Phase 3-ready precision cardiology asset from the Montreal Heart Institute, a leader in cardiology research.
Domain’s unique platform produced potential best-in-class assets against valuable GPCR targets, its lead assets demonstrated best-in-class data in the pre-clinical setting.
enGene’s lead program has competitive efficacy and safety data and a distinct delivery advantage, positioning it as the go-to treatment of choice for urologists.
Epitopea had a novel approach to identify tumor specific antigens that are highly immunogenic and shared across patients to enable true off-the-shelf cancer vaccines.
Find Therapeutics' platform that could design differentiated peptide-based therapies for intramembrane targets and its lead asset showed promising pre-clinical data.
Glycomine has a substrate replacement therapy that directly bypass the mutated enzyme in patients with PMM2-CDG; it is not only a first-in-class treatment but also the only disease modifying treatment.
Oligon is a pre-clinical biotech company developing the SeekR™ platform to enable self-delivering siRNA therapies beyond the liver.
Phenomic AI’s platform integrates one of the world's largest single-cell RNA (scRNA) datasets from human tissues, enabling the analysis of complex cell-cell interactions within multi-cell systems.
Profound’s MRI guided ablation not only improves survival outcome but is also significantly less invasive compared to traditional approach.
Thryv has a first-in-class treatment for a rare pediatric cardiology disease called Long QT Syndrome that demonstrated strong efficacy signal in its Phase 2a study.

Exited Companies

See portfolio
Amolyt’s parathyroid receptor agonist is specifically designed to bind to the calcium channel in the kidney and not in the bone, thus restoring serum calcium level without affecting deteriorating bone.
Enobia had a first-in-class disease modifying treatment for a rare and life-threatening pediatric disease called hypophosphatasia.
GLyPhama was created based on a deprioritized and highly de-risked asset from Ferring with best-in-class potential for treating short bowl syndrome.
Medicago’s plant-based platform had significant speed and cost advantages compared to traditional protein and vaccine production methods.
TargeGen's lead asset was being developed for myelofibrosis and polycythemia vera, conditions without approved therapies at the time.
Vaxcyte had the best-in-class pneumococcal conjugate vaccine (PCV) for pneumococcal disease which would make Vaxcyte and attractive target for current PCV marketers.
VectivBio's GLP-2 analog had significant competitive advantages against other GLP-2 assets, and can be used in a more broad short-bowl syndrome population.
Visterra had a proprietary technology platform, Hierotope, to design precision biologics that specifically bind to and modulate key disease targets.
Zymeworks had two innovative rationale design platforms – Azymetric and Zymelink, for rationale design of antibody-based treatments.